Tiagabinum [Inn-Latin]
Brand names,
Tiagabinum [Inn-Latin]
Analogs
Tiagabinum [Inn-Latin]
Brand Names Mixture
Tiagabinum [Inn-Latin]
Chemical_Formula
C20H25NO2S2
Tiagabinum [Inn-Latin]
RX_link
http://www.rxlist.com/cgi/generic/gabitril.htm
Tiagabinum [Inn-Latin]
fda sheet
Tiagabinum [Inn-Latin]
msds (material safety sheet)
Tiagabinum [Inn-Latin]
Synthesis Reference
No information avaliable
Tiagabinum [Inn-Latin]
Molecular Weight
375.55 g/mol
Tiagabinum [Inn-Latin]
Melting Point
No information avaliable
Tiagabinum [Inn-Latin]
H2O Solubility
No information avaliable
Tiagabinum [Inn-Latin]
State
Solid
Tiagabinum [Inn-Latin]
LogP
3.417
Tiagabinum [Inn-Latin]
Dosage Forms
No information avaliable
Tiagabinum [Inn-Latin]
Indication
For the treatment of partial seizures
Tiagabinum [Inn-Latin]
Pharmacology
Tiagabine is used primarily as an anticonvulsant for the adjunctive treatment of epilepsy. The precise mechanism by which Tiagabine exerts its antiseizure effect is unknown, although it is believed to be related to its ability to enhance the activity of gamma aminobutyric acid (GABA), the major inhibitory neurotransmitter in the central nervous system. Tiagabine binds to recognition sites associated with the GABA uptake carrier. It is thought that, by this action, Tiagabine blocks GABA uptake into presynaptic neurons, permitting more GABA to be available for receptor binding on the surfaces of post-synaptic cells.
Tiagabinum [Inn-Latin]
Absorption
Tiagabine is nearly completely absorbed (>95%).
Tiagabinum [Inn-Latin]
side effects and Toxicity
No information avaliable
Tiagabinum [Inn-Latin]
Patient Information
No information avaliable
Tiagabinum [Inn-Latin]
Organisms Affected
Humans and other mammals